Remifentanil vs. epidural analgesia for the management of acute pain associated with labour. Systematic review and meta-analysis
Abstract
Introduction: Remifentanil has an attractive pharmacological profile for use in obstetric analgesia as a technique for mass application, with similar benefits and satisfaction as epidural analgesia.
Objective: To assess the efficacy, equivalence and safety of remifentanil vs. epidural analgesia in obstetrics.
Methods: Systematic review and meta-analysis of clinical trials using the Cochrane methodology.
Results: No equivalence was found in relation to epidural analgesia; however, efficacy was found in the remifentanil group at different time points during the evaluation. The incidence of adverse effects was similar in the two groups, except for nausea.
Conclusions: Remifentanil is not equivalent to epidural analgesia but could certainly decrease the intensity of pain.
References
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